... Dosepak, - Safe combination for a 75 year old woman? Prior medication she was taking was Citalopram, Dexamethasone, Diphenhydramine, Docusate, Lorazepam, Metaxalone, Simvastatin, Tramadol, Combivent, and Mapap. Can any of the drugs cause legs to give out, muscle damage, or ligament damage? She also, has allergies to Morphine and Codeine.