Zoloft - what else can I take for depression. I feel it doesn't work for me?

5 May 2011

Hey Swild,

There are numerous antidepressants from which to choose. You may benefit from another serotonin reuptake inhibitor (SSRI) which is what Zoloft is or you may need a serotonin norepinephrine reuptake inhibitor (SNRI). Other SSRI's include Paxil, Prozac, Celexa and Lexapro while SNRI's include Cymbalta, Pristiq and Effexor. There is also Wellbutrin which targets the brain chemical dopamine. I take Pristiq with Wellbutrin and have had good results with this combo. There are just so many to choose from and unfortunately it is a trial and error sort of ordeal. Your doctor is the best to advise you what might work for you as he/she is most fimilar with your particular conditions.

Have the doctor explain the different types of antidepressants and ask him/her to try a different one. You can taper off the Zoloft while starting on the new one. It really is a simple process.

Best wishes,

Laurie

6 May 2011

There are just so many antidepressants currently on the market, that there is no reason to settle for a med that has side effects. Cymbalta makes some sleepy, if that's a problem, then maybe Pristiq as it generally speaking doesn't cause sedation. If the Zoloft was one of the few that helped the depression, but feel sedated, then Welbutrin can be added on in conjunction. If Zoloft isn't helping with the depression altogether, then either the dose needs to be changed, or a similar drug needs to be given a try such as Celexa or Lexapro. Realistically your doctor should know your best options available to you, and if you're seeing a primary doctor, I'd really suggest seeing a psychiatrist instead, as this is the class of drugs that they specialize in. You have to remember that there aren't just the SSRI's and SNRI's, but there's also the TCA's as well as a few atypical meds.

Good luck, and hope that you're able to work out a better situation!
Sincerely,

Jeff K