If a patient is allergic to Heparin should the be given Activase?
15 Nov 2009
You must tell your doctor you are taking Activase.
This is from the drugs.com interaction checker http://www.drugs.com/interactions-check.php
"... Alteplase is contraindicated in patients with acute ischemic stroke who have received heparin within the last 48 hours and have an elevated activated partial thromboplastin time (aPTT). Patients who are to receive a thrombolytic plus heparin for other indications should be carefully selected according to recommended eligibility criteria. The heparin dosage should be adjusted as appropriate to maintain therapeutic aPTT values. Patients should be closely monitored for signs of bleeding, especially at arterial puncture sites. Thrombolytic and/or anticoagulation therapy should be discontinued immediately if serious or uncontrollable bleeding occurs."
15 Feb 2012
You really need to provide more details. There is a big difference between Heparin and Activase. Typically Activase is used after a heart attack or stroke. Typically in a hospital setting, Argatroban is used in place of Heparin if you are allergic to it. Your other option for home use is Arixtra. Hope this helps.
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