I was taking the drug Avandia for about 4 years. I developed a blockage of AOD artery in my heart.?

It is unfortunate that no one has responded but there is a possibility that Avandia caused your condition.

Please see information below.

Important information about Avandia

Taking Avandia may increase your risk of serious heart problems, such as heart attack or stroke. Therefore, Avandia is available only to certain people with type 2 diabetes that cannot be controlled with other diabetes medications.

Do not use Avandia if you have type 1 diabetes, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Before taking Avandia, tell your doctor if you have congestive heart failure or heart disease, a history of heart attack or stroke, liver disease, or eye problems caused by diabetes.

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Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Always keep a source of sugar available in case you have symptoms of low blood sugar.

Some women using Avandia have started having menstrual periods, even after not having a period for a long time due to a medical condition. You may be able to get pregnant if your periods restart. Talk with your doctor about the need for birth control.

Women may also be more likely than men to have bone fractures in the upper arm, hand, or foot while taking Avandia. Talk with your doctor if you are concerned about this possibility.

http://www.drugs.com/avandia.html