I have tried almost every med out there and have terrible side effects... 40 pound weight gain on seroquel... I am just now fitting into my clothes after being stuck in a bathrobe and sweats. I read about the weight gain and am wondering since I also take adderall (30 mg a day) if that will help combat the weight gain issue of this drug? I also take 20 mg of lexapro, 300 mg of trileptal 2 mg Xanax (as needed) and 3 mg lunesta. I never heard of this drug before today. The reviews on here are excellent though. And my insurance WILL cover it, after seeing the cost I was even more apprehensive.