... I'm 19 and I do like to sometimes go out on weekends with friends or have some drinks. But on weekdays I never have any alcohol. But I'm always afraid when I'm out now how much is ok to drink. When I did drink now sometimes it feels like I'm drunk right away or sometimes I feel like I'm going to pass out after just one. Does anyone know if its ok to consume alcohol or how much when you are on the medication? Or does anyone else get weird symptoms while out?
15 Apr 2011
The literature recommends the following:
ethanol ↔ lisdexamfetamine
Applies to: Alcohol (contained in alcoholic beverages) (ethanol), Vyvanse (lisdexamfetamine)
GENERALLY AVOID: Ethanol may potentiate the cardiovascular effects of amphetamines. The exact mechanism of interaction is unknown. In one study, concurrent administration of methamphetamine (30 mg intravenously) and ethanol (1 gm/kg orally over 30 minutes) increased heart rate by 24 beats/minute compared to methamphetamine alone. This increases cardiac work and myocardial oxygen consumption, which may lead to more adverse cardiovascular effects than either agent alone. Subjective effects of ethanol were diminished in the eight study subjects, but those of methamphetamine were not affected. The pharmacokinetics of methamphetamine were also unaffected except for a decrease in the apparent volume of distribution at steady state. The interaction was suspected in a case report of a 20-year-old male who experienced retrosternal chest pain shortly after drinking alcohol and taking a double dose of his amphetamine/dextroamphetamine medication (Adderall 15 mg X 2) to stay alert. The patient had no family history of cardiovascular diseases, and his past medical history was remarkable only for ADHD. Prior to the episode, the patient had not taken his medication for weeks and had been drinking whiskey the previous three nights before going to bed. The patient was diagnosed with myocardial infarction likely secondary to amphetamine-induced coronary vasospasm.
MANAGEMENT: Concomitant use of amphetamines and ethanol should be avoided if possible, especially in patients with a history of heart disease.
So it might be a good idea to avoid the alcohol while taking Vyvanse. Don't want you to hurt your heart.
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