Cramps that go from my big toe up to my groin, waking up during the night - I'm always awake by 5.30 which is no good at all, as Ir arely get to sleep before 1am, and total lethargy - I have just done my ironing after 4 weeks. Am so fed up with it, but it does help with my back pain. I am also taking tramadol for pain relief, along with 13 other drugs daily.