I have duodenal ulcer,i went to a doctor and he done endoscopy and suggested me some medicines. but?

7 Nov 2009

Domperidome can cause lactation. Please see your doctor.

Domperidone is a dopamine antagonist with antiemetic properties. Domperidone does not readily cross the blood-brain barrier. It seldom causes extrapyramidal side effects, but does cause a rise in prolactin levels. Its antiemetic effect may be due to a combination of peripheral (gastrokinetic) effects and antagonism of central dopamine receptors in the chemoreceptor trigger zone which lies in the area postrema and is regarded as being outside the blood-brain barrier.

Domperidone produces an increase in plasma prolactin, which causes that lactation. The raised level persists with chronic administration but falls to normal on discontinuing the medicine.

http://medsafe.govt.nz/profs/datasheet/m/motiliumtab.htm

27 Jan 2010

I am also taking domperidone for gastroparesis and it does cause discharge from the nipples, swollen/tender/enlargement of breasts, and many other side affects.

It may be perfectly fine to continue the domperidone, but you should let your doctor know that you are having side affects.