... toe) to intravenous nafcillin which occurred at the 4 week point. After 2 doses of Cubicin being delivered intraveneously he is experiencing serious swelling of the feet and lower legs. I've called the prescribing doctor twice and his only suggestion was to take him to the emergency room. After the last two doses he has begun excreting a clear liquid from his legs. His urine output has been normal and he has no fever