13 Nov 2009
It's usually taken until the patient has shown significant improvement in depression. If you are trying to stop taking it, but have been on it for a while; you need to talk to your doctor about tapering off of it instead of stopping it cold turkey. If you discontinue the med abruptly, it can cause severe nausea and vomiting as well as severe headaches. If you are simply wondering how long it takes for Zoloft to be effective, then you should know that it takes about 1-2 weeks before you notice any marked improvement. Hope this helps.
- Sertraline Information for Consumers
- Sertraline Information for Healthcare Professionals (includes dosage details)
- Side Effects of Sertraline (detailed)
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By long term I mean over a period of several years.
1 answer • 27 May 2010
I am taking sertraline for 13years and it really does help exept for sweating problems and breathing probelms when making efforts
1 answer • 30 May 2011
I have been on sertraline nearly 9weeks now n I still don't see any major improvement,how long does it take to actually work.
1 answer • 10 Jul 2013
how long is the affect from sertraline? would it be a full 24 hours?
1 answer • 21 Jan 2015