9 Sep 2010
The recommended daily dose of Plavix is 75 milligrams once a day. To give people with unstable angina an extra boost, their first dose is usually increased to 300 milligrams. Anything more than this is too much.
After a single, oral dose of 75 mg, Plavix (clopidogrel) has a half-life of approximately 6 hours. The half-life of the active metabolite is about 30 minutes.
It takes 5.5 x half-lifes of a medicine for it to be out of one's system. So Plavix should be cleared from your system in about 5.5 x 6 hours = 33 hours.
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