I have been taking it for about 2 months, but I find I am generally feeling unwell and still in pain--I don't like feeling worse to feel better- I thought arthritis was an autoimmune disease, so impairing myself even more seems like unneeded suffering--is this drug really worth it? So far not for me.
How long does it take to experience pain relief from methotrexate?
Added 26 Mar 2010:
I am taking a folic acid supplement daily--I am just concerned about the side effects of this drug, since I feel sick a lot now, and no pain relief yet, and extra stomach sensitivity. Would taking a supportive supplement such as Bovine Colostrum or herbal echinacea& goldenseal w/vit.C interact with the effectiveness of methotrexate for rheumatoid arthritis?
26 Mar 2010
For the treatment of rheumatoid arthritis, patients should supplement their diet with folate. In these cases inhibition of dihydrofolate reductase (DHFR) is not thought to be the main mechanism, but rather the inhibition of enzymes involved in purine metabolism, leading to accumulation of adenosine, or the inhibition of T cell activation and suppression of intercellular adhesion molecule expression by T cells.
This diet is extremely important and you really need to following... Dave
- Methotrexate Information for Consumers
- Methotrexate Information for Healthcare Professionals (includes dosage details)
- Side Effects of Methotrexate (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
I already take 15mg of methotrexate but I still have pain and need to take anti inflamatory drugs on
... top. Does anyone know if the methotrexate will eventually allow enough of the disease to be blocked so that there is no need to take any other ...
2 answers • 14 Sep 2009
I was diagnosed with RA in Feb 2010-started on prednisone 10mg ended up going to 40mg with little relief-started on paquinel and methotrexate ...
2 answers • 4 Nov 2010
Could really use some help ... When it flares up it is unbelievably painful and literally takes your breath away when it is at its worse and it can ...
2 answers • 6 Mar 2012
I had only been taking MTX for about 2 months and had to stop due to extreme sun-sensitivity that started on the same week that I went from 10mg/wk ...
3 answers • 8 Jan 2013
I have a friend who has had neuropathy since being rear ended in 1991. @ back surgs. no relief. Started Lyrica about a week ago. Pain gone, be he ...
2 answers • 28 May 2014