13 Mar 2010
The mean time to peak plasma concentrations (Tmax) of carisoprodol is approximately 1.5 to 2 hours. Co-administration of a high-fat meal with carisoprodol (350 mg tablet) had no effect on the pharmacokinetics of carisoprodol. Therefore, carisoprodol may be administered with or without food.
Metabolism: The major pathway of carisoprodol metabolism is via the liver by cytochrome enzyme CYP2C19 to form meprobamate. This enzyme exhibits genetic polymorphism (see Patients with Reduced CYP2C19 Activity below).
Elimination: Carisoprodol is eliminated by both renal and non-renal routes with a terminal elimination half-life of approximately 2 hours. The half-life of meprobamate is approximately 10 hours.
- Soma Information for Consumers
- Soma Information for Healthcare Professionals (includes dosage details)
- Side Effects of Soma (detailed)
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1 answer • 14 Jan 2011
What other prescription muscle relaxers are on the market? Is Soma a muscle relaxer? I believe I heard it was no longer going to be made - is this ...
26 answers • 6 Jul 2011
My pain management dr had me on Soma but the last time I went he was no longer with their clinic. The other drs in the clinic are no longer writing ...
4 answers • 1 Aug 2013
1 answer • 7 Nov 2013
My pain dr does not prescribe Soma at all but is willing to prescribe Zanaflex 2mg. What mg of zanaflex should I be on to equal the same strength of ...
1 answer • 15 Feb 2014