I have taken Rituxin with no improvement in platelet counts and Prednisone which has done a number on my weight and bones. Also had a splenectomy which kept my count up for year. My counts are now below 50 again.
5 Sep 2011
"The mechanisms of action of danazol are unclear but involve impairment of macrophage-mediated clearance of antibody-coated platelets via decreased Fc
Or put a little simpler danazol reduces the ability of the body to remove platelets from the blood.
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as a second line of treatment after prednisolone ,which did not respond
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