I have been given 120 mg/day of Cymbalta (2 @60 mg) per day for depression and Fibromyalgia. Also, 300 mg 'long-acting' Tramadol plus extra 'short-acting' Tramacet per day for Fibromyalgia. I believe I may have been suffering from Seratonin Syndrome /toxicity for a while now (at least 3 months). Symptoms: sweating, goosebumps, clamminess, muscle 'jerking' and spasms, tremors, In the last 3 days I have weaned myself down to 60 mg Cymbalta per day and 100 mg Tramadol. My sweats/tremors have eased although I still have elevated body temp. It was my pharmacist who alerted me to the high dosage of Cymbalta and when I described my symptoms she suggested Seratonin Syndrome.
Hello, My name is Sheri and I would like some advice on how to wean off of Tramadol and Cymbalta?
- Posted:
- 7 Feb 2012 by sherianne321
- Topics:
- cymbalta, depression, fibromyalgia, tramadol
Details:
Answers (2)
LaurieShay7 Feb 2012
Yes it is quite possible you were experiencing serotonin syndrome. To taper off the cymbalta I would stay at the 60mg for another week then go to eveyother day for at least a week before stopping. To taper off the tramadol, I would work with the short-acting tramacet as you can not split the 100mg long-acting tramadol in half. Reduce from your 100mgs a day by 25mg increments every week. If you have the 50mg tramacet you can accomplish this by splitting the pills and reducing your daily intake by 25 mgs every week until you are down to 25mgs for a week, then split the 25mgs halves into 12.5 mg pieces and take once daily for a week.
9 Feb 2012
I was on cymbalta for approximately 2 months for depression and peri-neuropathy, I was experiancing some of the same things you are describing! If you read the entire inserts - you will realize that a lot of your symptoms are side affects! I developed a pancreas problem as well as my blood becoming to thick. I would recommend weaning off of your cymbalta, while continuing your tramadol then weaning off of the tramadol. Weaning both will not only leave you in a lot of pain but withdrawals as well!
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Please discuss weaning off these medications before you do anything else with a physican. A physician who knows you will let you know what is the best way to taper off the medications. You are taking high doses of both and I would hate to see your system crash. Since you have a history of depression it is vital the doctor decides the best way to taper. Sometimes they will switch to a different medication with lower dosage and less side effects. He might also want to assess your depression status as you go. Sometimes you need to stay on a lower dose longer while your body adjust to the changes. Cymbalta can be a difficult medication to wean off of. I would also talk to the doctor regarding the sertonin syndrome symptoms. Weaning to fast might make these symptoms worse. I find it vital to seek medical advise from your physican when your tapering. This website is wonderful and the advise we all can give is helpful. But I am a nurse and I find what your doing too important not to seek the physicans advise that is treating you!
Good luck!
Sheila7281