When I was on a cruise I applied a scopolamine patch to avoid motion sickness and about 16 hours later I had an episode of severe vomiting (7 -8 times in a couple of hours) followed by fainting several times and having to get emergency help and rehydration. I could not fine any reference to such a reaction. I was taking no other medication at the time. I had no diarrhea or lower intestinal problems (as in food poisoning).