I have been treated for depression for over 20yrs and now have severe major depression for last 6 months. I take 150 mg Effexor XR and it doesn't seem to be working. I also have anxiety and panic attacks.
19 Jun 2012
Hi, I have Bipolar 2 which the last person mentioned as well, and I too have had amazing results with Lamictal added to Wellbutrin, and Zoloft. I also have anxiety issues so that why I take both antidepressants.Although for many years Wellbutrin somewhat helped my depression by itself,it was not enough, & that when I was finally diagnosed Bipolar 2. I have had to adjust doses a little bit here and there, but overall I have felt good. I sincerely hope you can find relief, I know how hard it can be just to function at a minimal level..I would keep trying different drugs but most importantly, make sure both you & your Psych/Counselor is really communicating well, otherwise find another one that you "click" with.. Remember, they are supposed to work with you and for you, not treat you like just another number.. JT
31 Jul 2012
I have severe depression too and take Celexa 20 mg. I think we will be moving up to 40mg though on my next visit. It has seemed to work very well for years
now, but it does tend to "wear off." Then you have to switch and every time I do that I end up more depressed. So, Celexa is the best for me personally.
Not sure if you have ever tried that one???
I also take Xanax for anxiety. Works wonders!
I hope that helps. If you have any other questions please feel free to email me.
10 Nov 2012
Wellbutrin and lexapro work wonder for me i have to be commited for evaluation i was so depressed and the to worked so well.my dr added the lexapro about a month later be cause my seratonin levels would stoll drop but after thr lexapto im good the same thing for a fellow crazy of mind . Just in good humor you cant have enougj of that so i like to tell people i meet with the same sympton that they are one of the crazies make me lafe and not hide from what we are
5 May 2013
Hi. I have had major depression as well as anxiety and panic attacks . I have been on Effexor but it didn't work well for me either. So I was switched to Cymbalta. That worked well, but after being on it for a long period of time , I think it stopped working as well . (very bad withdrawals from that -google it.) I then went on Celexa which I really like. It works really well . I take 40mg per day and no side effects at all. I would highly recommend it as one of the best. For anxiety , I've always been on Klonopin 1 mg several times per day. I was on Buspar for a period of time as well 15mg 2x day.
19 Jun 2012
Hi PNHHM -
Since we haven't heard back from you in a while, I am just writing to see if you are okay. I hope that some of the suggestions that we gave you have helped and that you have discussed all possibilities with your psychiatrist. I hope you have a good psychiatrist or psychopharmacologist and not a GP. When it comes to matters of the "head"; the best resource is one who really understands the medication and mental health issues.
I wish you well and much enlightenment on your journey.
13 Jul 2013
I also suffer from very serious depression and I have been prescribed many many different depression medications and the only 2 medicine's that has ever worked for me are Prozac that also caused me to have chronic migraines but helped the depression. The other medication that has fixed every sign and symptom of depression is not exactly prescribed for depression but worked the best is percocet which is prescribed for pain.
13 Aug 2012
To answer the question, I believe there is no such medicine available. There is no one size fits all solution. The psychiatrist in most cases will try one medicine and will monitor the effectiveness of that medicine within a specific time frame. If the patient feedback is negative whether due to unpleasant side effects or no change in his/her condition, the psychiatrist may increase the dosage, or replace it with a new medicine in a similar or different class of medicines. Some times he may augment the prognosis with an off-label medicine but this is rarely done unless its for cases that are resistant to traditional treatments. One point to note always is, the treatment plan outlined by the psychiatrist is very much based on the patients reaction to the medicine and such treatments must always be based with the psychiatrist always be kept in the loop.
26 Jul 2012
i suffer from major depression severe. so far my course has been welldutrin(bupropion) which worked for alittle while until i had a seizure. zoloft(sertraline) which worked shortly abilify which made me gain weight now i take effexor and amantadine so i really don't know what works its just trial and error but thats what ive tried so far i hope this helps
13 Aug 2012
I have been suffering from depression & anxiety attacks for 25 years now. I was prescribed an ssri and to this day I am still on the same ssri although there were slight changes in dosage made by the doctor.
To answer your question, I believe there is no such medicine available right now as there is no one size fits all in such cases using psychotropic medicines.
The doctor will usually prescribe a certain medicine to treat a specific or a combination of disorders within a certain time frame. If the feedback from the patient is negative such as unwanted side effects or no therapeutic responses from the medicine, the doctor may then increase the dosage or replace the medicine with another medicine from the same or different class of medicines. The doctor may also use an off-label medicine to augment or to treat very resistant-prone depressive symptoms. It is very important and pertinent that such treatment must always be done under the care or supervision of a doctor and requires & necessitate that the doctor should always be kept in the loop during such treatments.
21 Sep 2012
For years, I have battled with depression and severe anxiety. I was put on a combo of Zyprexa and Prozac and it seems to be helping. It comes in one pill form now. It is marketed for treatment resistant depression. I know everyone reacts different to certain meds. I hope things improve for you. As for effexor, it was hell coming off of that... just my reaction.
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