sir my self jyoti sharma i am persuing m.pharmacy for my research work i got gemcitabine hydrochloride so can you tell which which type of formulation can be prepare with gemcitabine
1 Aug 2012
The clinical formulation is supplied in a sterile form for intravenous use only. Vials of Gemzar (gemcitabine hcl) contain either 200 mg or 1 g of gemcitabine HC1 (expressed as free base) formulated with mannitol (200 mg or 1 g, respectively) and sodium acetate (12.5 mg or 62.5 mg, respectively) as a sterile lyophilized powder. Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment.
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