While using it my right knee swelled up and I had such severe pain I could not bend my knee. Had severe pain when trying to sit one get back up. Could not lift it to get into car or bath tub. Also caused it to ache while sitting at a table. When I quit using it it got better Immediatly, but took about three months for my knee pain to go away. It was the only time I've had swelling of my knee. My doctor says it is impossible for it to be caused a by Flovent. I, obviously, don't agree.