I take 10 mg of Amlodipine once daily in the morning, I understand grapefruit and beta blockers do not "get along". But Amlodipine is a calcium channel blocker, so am I okay to eat grapefruit or should I avoid it?
23 May 2013
There is a minor interaction,meaning:
The consumption of grapefruit juice may slightly increase plasma concentrations of amlodipine. The mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruits. Data have been conflicting and the clinical significance is unknown. Monitoring for calcium channel blocker adverse effects (e.g., headache, hypotension, syncope, tachycardia, edema) is recommended.
Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Always consult with your DR. or Pharmacist/Chemist.
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
1 answer • 12 Aug 2012
If I am using AMLODIPINE TAB 50 mg for blood pressure and also Timolol MAL OPTH SOL 0.5%, is this perhaps too much beta blockers? Maybe only 1 is ...
1 answer • 25 Mar 2013
I was recently given an RX for HBP. In reading about the drug prescribed, Benazepril HCL, 40mg, it says it is a "calcium channel blocker." ...
1 answer • 5 May 2013
I think I may have developed this cough that I've heard about. I am on both metoprolol (beta blocker) and exforge (amlodipine (calcium channel ...
1 answer • 30 Sep 2013
... I take a calcium channel blocker and an ACE inhibiter can you add a beta blocker to this mix (verapamil and lisinopril)
2 answers • 4 Oct 2013