Does morphine extended release 30mg, typically cause headaches?

I am also on extended release morphine 30 mg that I take twice a day. I started morphine in April and I would get a headache shortly after taking it and it would last most of the day. The headaches continued for 2 months but shortly after that, they stopped. I was very happy about that because the morphine has helped my chronic pain greatly.

I would give your body some time to get used to the morphine. I would say if you still have a headache after 3 months of taking it, you should look into a different medicine for pain. Because, I know how frustrating those headaches can be, let alone painful. And, like you said, nothing over the counter gets rid of them. I also take oxycodone instant release for breakthrough pain but I was on oxycodone before I started morphine and it didn't cause headaches. So oxycodone may be a better choice. They do have extended release oxycodone.

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I also agree with DzooBaby in reference to the increase in intercranial pressure. This is because morphine is a blood vessel dialator. Blood vessel dialation is probably the underlying cause of your headaches. But your body should eventually get used to the blood vessel dialation in 2-3 months, which should get rid of your headaches.

Hope that helps.