Does Diflucan interfere with birth control medications?

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9 Nov 2009

There is evidence that Diflucan (Fluconazole) can inhibit the metabolism of ethinyl estradiol and levonorgestrel, there is no evidence that fluconazole is a net inducer of ethinyl estradiol or levonorgestrel metabolism. The clinical significance of these effects is unknown.

You should use a back-up method while taking the Diflucan. I was told by my doctor that is can decrease the effectiveness of birth control, while taking it.

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