Does celebrex have to build up in your body before it works?

I used Celebrex for years with success,I had to stop using it when I developed liver problems due to a drug called nitrofurant.My liver symptoms have abated so I asked my Dr. to prescribe Celebrex again because I really need more relief from arthritus than I got from melexicam.I started taking it three weeks ago and did not feel better until yesterday.I don't know if that's a fluke or if its now working. thanx pl

Hey Mad Mad are ua Mad Man or r u just damn MAD at the lack of pain control going on?

I have tried all the other drugs/NSAIDS and Celebrex is the ONLY one that gives me any relief. I have been off it for too long. I WANT MY CELEBREX AND I NEED IT NOW!

I am sorry for shouting but I am having surgery on Monday and have to be off the Celebrex 10 days prior and I hate when they do this to me. Pain is pain and the Celebrex helps somewhat on a bad day and then they take me off of it because it is considered a blood thinner(or some such notion) and then all I feel is pain until the surgery. Crazy!