... has me taking 100 mg Topamax and 25 mg amitriptyline to prevent migraine frequency. I also take Axert to manage the pain of migraines, since OTC meds do not help at all (even hydrocodone does not help). The last severe migraine I had lasted for 2 months straight. Now they are less frequent, but the pain still gets so severe that it hurts to lay my head on my pillow. Is this normal?