In March switched from Vivaglobin to Hizentra for hypogammaglobulinemia related to multiple myeloma. No problems with Vivaglobin, but +/- once a month I form these nodules that last a couple of months and then go away. Two weeks ago switched from 3-site to 4-site, hoping to stop the nodules. Oncologist says the sites got inflamed and calcified. Not painful, but a little sore. Anyone else have this?
Does anyone else form hard, calcified nodules under the skin at the infusion sites with Hizentra?
- Posted:
- 8 Aug 2011 by kathyhanson
- Topics:
- primary immunodeficiency syndrome, multiple myeloma, hizentra, skin
Details:
Responses (1)
sand012530 Nov 2011
I also switched from Vivaglobin to Hizentra around the same time. I did not get as many nodules with vivaglobin. I felt that it spread out more under my skin than Hizentra does. I started to softly massage the injection site after my injections. It obviously hurts a tiny bit but it helps the liquid spread. Also, I was told if you put a heating pad on your sites it spreads faster too. I don't have a heating pad yet so I can't say how true it is. My nodules stay for weeks! I still have one from a month ago.
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It is good to know that it's not just my body that's doing weird things. My doctor doesn't understand why I get so many nodules, but I guess it's a small price to pay considering the alternative. Switching from 3 to 4 sites helped a little -- the nodules aren't as big. Thanks for the suggestion of massaging the infusion sites to spread the liquid. I hadn't thought of that. I have 4 nodules on my belly and 2 on my inner thigh from the last 2 months. At least I know they'll eventually go away.