Diflucan in breastfeeding?

Nystatin is very poorly absorbed into the bloodstream (even when taken by mouth) and as a result, is not expected to ever actually reach the breast milk (since medications must travel through the bloodstream before they can be passed through breast milk).

Additionally, nystatin is approved for use even in newborns. Therefore, it would not be dangerous for a newborn to be exposed to nystatin through breast milk (even though this is highly unlikely to occur).

For especially resistant thrush infections, nystatin is sometimes prescribed to both a breastfeeding mother and an infant. In this case, the infant is usually given nystatin oral suspension (liquid), and the mother is given nystatin cream for use on the nipples.

Nystatin ointment should not be used, since it could expose the infant to an unacceptably high level of petrolatum. Women are usually advised to wipe off any excess cream before each nursing session.

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Since your doc & the pediatrician has told you that Nystatin is ok, I guess you should be alright & so would your infant.

Take care, best wishes!

Here is what the manufacturer states about using Diflucan while breastfeeding:

Fluconazole is excreted into human milk. The effects in the nursing infant are unknown. The manufacturer recommends that caution be used when administering fluconazole to nursing women.

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Fluconazole is excreted in human milk at concentrations similar to maternal plasma levels. A nursing woman who received a single dose of fluconazole 150 mg orally to treat vaginal candidiasis had breast milk:plasma ratios of 0.46, 0.85, 0.85, and 0.83 at 2, 5, 24, and 48 hours, respectively, indicating relatively high concentrations of drug in the breast milk. The use of fluconazole has been documented in at least 2 neonates at a dosage of 6 mg/kg. One infant developed a small, transient elevation in liver function tests which resolved with a dosage reduction. These cases suggest fluconazole may be safely used during breast-feeding, as infants would receive significantly less drug. However, more experience is necessary to establish safety.

If your child's pediatrician states it is ok then it should be. Medicines are used for infants too.