Difference in different Watson Hyrdocodone pills?

Hi Mike,

I looked them up to make sure about this. But you are right, the only real difference is the amount of Tylenol, or acetaminophen in them. If you mean you feel better in terms of pain relief, then it's coming from the extra acetaminophen. For some reason acetaminophen and opiates amplify each other's pain relieving properties.

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If you mean you feel better emotionally with one of them, then you are one of the few people who is hypersensitive to small changes in a drugs make up. I'm like that. Be prepared to be called crazy by docs and pharmacists all your life. And I'm not just hypersensitive to drugs like opiates, I'm also hypersensitive to many other drugs too, such as some of the meds used for HBP. One of my HBP meds effects me differently when the pharmacy changes the brand on me. This causes quite a problem since I'm talking about my heart here. I noticed the 2 Watson pills you're referring to are different colors. Maybe the dye is effecting you. Or more likely the Hydrocodone is being manufactured in different labs, and minute differences in the chemical make up of the drug are making you feel different. The large majority of people do not feel such differences, but some of us do.

The drug companies have a vested interest in having us believe all drugs are made equally. But the sad truth is they are not. I suppose a top notch chemist would know why this is, but other than a chemist, I don't think any of us can say why this happens. But it does, and now that you know you're one of the few people who feel the differences, try to always get the pill that agrees with your system best.