Daughter took zofran second trimester pregnancy, was this safe for her to take for nausea? Baby Fine at one week old, just abnormal defect
10 Sep 2011
Zofran is safe to take during pregnancy (it's category B in the US).
Here's a great explanation of what the different Pregnancy categories mean, from the FDA (who assigns these letters) (source: depts.washington.edu/druginfo/Formulary/Pregnancy.pdf) You might need to download Adobe Reader (free online) to read this document.
"The FDA-assigned pregnancy categories as used in the Drug Formulary
are as follows:
Adequate and well-controlled studies have failed to demonstrate a risk
to the fetus in the first trimester of pregnancy (and there is no evidence
of risk in later trimesters).
Animal reproduction studies have failed to demonstrate a risk to the
fetus and there are no adequate and well-controlled studies in pregnant
Animal reproduction studies have shown an adverse effect on the fetus
and there are no adequate and well-controlled studies in humans, but
potential benefits may warrant use of the drug in pregnant women
despite potential risks.
There is positive evidence of human fetal risk based on adverse
reaction data from investigational or marketing experience or studies
in humans, but potential benefits may warrant use of the drug in
pregnant women despite potential risks.
Studies in animals or humans have demonstrated fetal abnormalities
and/or there is positive evidence of human fetal risk based on adverse
reaction data from investigational or marketing experience, and the
risks involved in use of the drug in pregnant women clearly outweigh
- Zofran Information for Consumers
- Zofran Information for Healthcare Professionals (includes dosage details)
- Side Effects of Zofran (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
I find promethazine does a wonderful job in controlling nausea, but also puts me to sleep for about 9-10 hours. My doctor says all anti-nausea ...
2 answers • 2 Aug 2010
I have been experiencing nausea w/o vomiting off and on for about a year. I never experienced anything like this in all of my life until I turned 70. ...
1 answer • 18 Dec 2011
What are the benefits of using zofran vs gravol?
1 answer • 13 Mar 2012
... Sometimes she has constipation. How can I help. She has 4mg ZOFRAN , but reduses to take it, says it never helped her. please give advice on ...
1 answer • 26 May 2014