I just started 30 mg, and am very happy with some relief of my depression and anxiety, but am too tired to function. I don't want to give up the drug. How long do the effects last? If I take it at night before I go to bed, will I still feel the positive effects the next day?
Can I take Cymbalta at night? It makes me too tired when I take it in the morning?
- 22 Apr 2012 by Prudence Sprite
- cymbalta, depression, anxiety, generalized anxiety disorder
Added 22 Apr 2012:
Since I also suffer from insomnia, I have been taking .05 mg of Clonipin, and 3 mg of Silenor to sleep. If I can take Cymbalta at night, which of the above should I taper off?
22 Apr 2012
Yes, the positive effects will last throughout the night and day whether you take it at night or in the morning. It builds to a certain level in your blood and as long as you take it on schedule it will be working. You may find after being on it for awhile that you'll want to change back to dosing in the morning as it can cause insomnia. Just gonna have to give it a try.
22 Apr 2012
I have tried taking it in the morning and at bedtime and I prefer taking it at bedtime to help me sleep. And if it makes you sleepy, by all means I recommend you to take it early in the evening so you won't be so "hung over in the mornings". I have chronic fatigue, as well as fibro and miss out on a couple of stages of sleep per my sleep study so I take almost all of my meds at night and still don't sleep very well. Good luck!
22 Apr 2012
From what I can see, Silenor isn't a good mix with Cymbalta since it can cause serotonin syndrome. If you check the "symptom checker" at the top of this web site you can see more details about the mix. I'm not sure what the other drug is you're taking. I tried 30mg of Cymblata at night first because it can cause drowsiness but the insomnia was so severe I had to switch to mornings. After a few days I was less tired and now feel my "normal" tired again(I'm always so very tired so it's a bit hard for me to tell what's doing it). So may be worthwhile trying it for a few days. I also take Ativan and Zopiclone for insomnia.
- Cymbalta Information for Consumers
- Cymbalta Information for Healthcare Professionals (includes dosage details)
- Side Effects of Cymbalta (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
I have been on 60mg Cymbalta bid for several years. My bipolar 2/generalized anxiety disorder has been very well controled. Now my primary doctor ...
7 answers • 1 Feb 2010
I recently was prescribed Cymbalta 20mg and Ambilify 5mg I took the Cymbalta first in the morning and a few hours later I was very anxious and ...
2 answers • 18 Jan 2012
My dr., just prescribed cymbalta 30 mg for my depression. I have been on brintellex 10 mg., and fell
... into a deeper depression. How has cymbalta helped you with depression and anxiety. Hoping to get out of this soon and leave the dark cloud ...
3 answers • 12 Feb 2015