I have been prescribed both tablets and been taking it for a year and have now been told by another doctor I dont need to take both I suffer from Trigeminal Nearalgia
23 Nov 2010
Interactions between your selected drugs
carbamazepine ↔ gabapentin
Applies to: Tegretol (carbamazepine), Neurontin (gabapentin)
MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.
MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
Other drugs that your selected drugs interact with
Neurontin (gabapentin) interacts with more than 100 other drugs.
Tegretol (carbamazepine) interacts with more than 400 other drugs.
Interactions between your selected drugs and food
carbamazepine ↔ food
Applies to: Tegretol (carbamazepine)
GENERALLY AVOID: In a small, randomized, crossover study, the administration of carbamazepine with grapefruit juice (compared to water) increased plasma drug concentrations by approximately 40%. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruits.
MANAGEMENT: Given the drug's narrow therapeutic index, patients receiving carbamazepine therapy should preferably avoid the regular consumption of grapefruits and grapefruit juice to prevent any undue fluctuations in plasma drug levels. Patients should be advised to report signs of carbamazepine toxicity (nausea, visual disturbances, dizziness, or ataxia) to their physicians.
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