Can we infuse propofpl and remifentanil in one syringe?

Here is what I found in literature re:propafol

Compatibility and Stability: DIPRIVAN (propofol) Injectable Emulsion should not be mixed with other therapeutic agents prior to administration.

Dilution Prior to Administration: DIPRIVAN (propofol) Injectable Emulsion is provided as a ready- to-use formulation. However, should dilution be necessary, it should only be diluted with 5% Dextrose Injection, USP, and it should not be diluted to a concentration less than 2 mg/mL because it is an emulsion. In diluted form it has been shown to be more stable when in contact with glass than with plastic (95% potency after 2 hours of running infusion in plastic).

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Administration with Other Fluids: Compatibility of DIPRIVAN (propofol) Injectable Emulsion with the coadministration of blood/serum/plasma has not been established. (See WARNINGS.) When administered using a y-type infusion set, DIPRIVAN (propofol) Injectable Emulsion has been shown to be compatible with the following intravenous fluids.

5% Dextrose Injection, USP
Lactated Ringers Injection, USP
Lactated Ringers and 5% Dextrose Injection
5% Dextrose and 0.45% Sodium Chloride Injection, USP
5% Dextrose and 0.2% Sodium Chloride Injection, USP

Here is what I found about remifentanil

Compatibility With Other Therapeutic Agents: ULTIVA (remifentanil) has been shown to be compatible with DIPRIVAN® (propofol) Injection when coadministered into a running IV administration set. The compatibility of ULTIVA (remifentanil) with other therapeutic agents has not been evaluated.

So it can be given together if you are running an IV. I could not find anything on administering together in a syringe.

You might consult a pharmacist for a better answer.