21 Apr 2011
if you are taking it for pain it should be no problem. but i am no doctor so make sure you check in with them first. i was on suboxen for 6 months and it worked great, you didn't get loopy or high. the only thing it did do was give me migrains that is why is stopped taking it. i hoped this helps if so please check yes at the end of this answer so i know i was helpful, your friend if needed amber
21 Apr 2011
Not trying to be evasive, but I would ask the opinion of a pharmacist on this particular question, I would think off hand that subutex might be better, but since people who have hep c have a weakened liver, then less medicine going thru it, the better. Subutex only has one of the meds in it, not the second med, which is naloxone, other than that, it is the same as suboxone.Pharmacists are really experts on medication, and likely would be able to tell you how rough the suboxone or subutex would be for the liver to metabolize. Pattishan
21 Apr 2011
The literature points out the following about Suboxone:
Hepatitis, Hepatic Events
Cases of cytolytic hepatitis and hepatitis with jaundice have been observed in individuals receiving buprenorphine in clinical trials and through post-marketing adverse event reports. The spectrum of abnormalities ranges from transient asymptomatic elevations in hepatic transaminases to case reports of death, hepatic failure, hepatic necrosis, hepatorenal syndrome, and hepatic encephalopathy. In many cases, the presence of pre-existing liver enzyme abnormalities, infection with hepatitis B or hepatitis C virus, concomitant usage of other potentially hepatotoxic drugs, and ongoing injecting drug use may have played a causative or contributory role. In other cases, insufficient data were available to determine the etiology of the abnormality. Withdrawal of buprenorphine has resulted in amelioration of acute hepatitis in some cases; however, in other cases no dose reduction was necessary. The possibility exists that buprenorphine had a causative or contributory role in the development of the hepatic abnormality in some cases. Liver function tests, prior to initiation of treatment is recommended to establish a baseline. Periodic monitoring of liver function during treatment is also recommended. A biological and etiological evaluation is recommended when a hepatic event is suspected. Depending on the case, SUBOXONE sublingual film may need to be carefully discontinued to prevent withdrawal signs and symptoms and a return by the patient to illicit drug use, and strict monitoring of the patient should be initiated.
While the above information does not rule out using Suboxone for hepatitis patients, it does suggest caution be used. I would discuss this thoroughly with a prescribing doctor before initiating treatment with Suboxone.
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