Can I eat grapefruit while taking coumadin?

Answers (2)

8 Mar 2011

Yes, it is safe for you to consume grapefruit while taking Coumadin. No known serious dug interactions exist.
http://www.drugs.com/interactions-check.php?drug_list=2624-0,2311-1529

Votes: +0

17 Aug 2011

NO, grapefruit is NOT recommended concurrently with warfarin (brand name Coumarin). The warfarin prescribing information (aka PI: the *official*, FDA-approved information that accompanies the product) describes how the drug is metabolized by the cytochrome P450 pathway. The furanocoumarin compounds in grapefruit interfere with the enzymes in the P450 cascade. Thus, grapefruit consumption will cause warfarin to remain in your body longer (because warfarin metabolism is delayed for up to 72 hours after eating/drinking the grapefruit), and your PT/INR level will rise.

Votes: +0

Further Information

Search for questions

Still looking for answers? Try searching for what you seek or ask your own question.

Similar questions

Prosthetic Heart Valves -- Mechanical Valves - My husband is taking lovenox following a mechanical?

... replacement of his aortic heart valve. Is there a study of the effectiveness of Plavix and a baby aspirin instead? (had problems with coumadin)

1 answer 11 Mar 2010

Hi Friends! I have a mechanical heart valve, on Coumadin for life, and?

I'm building a list of Drugs that interact with Coumadin. I've had a few bad internal bleeds that almost took my life. I have the list ...

1 answer 18 Aug 2010

Prosthetic Heart Valves -- Mechanical Valves - I had a mechanical heart valve implant in Dec. 2010.?

... How long does it take to feel normal? I feel like a time bomb waiting to go off. I have a very hard time sleeping because I can hear the ticking ...

3 answers 22 Oct 2011

Prosthetic Heart Valves - Mechanical Valves - My doctor has said NO Alcohol for me with my?

... artificial (mechanical) heart valve but I see other people talking about a glass of wine or an occasional beer or two is OK. What's up with ...

1 answer 16 Aug 2014