8 Mar 2011
Yes, it is safe for you to consume grapefruit while taking Coumadin. No known serious dug interactions exist.
17 Aug 2011
NO, grapefruit is NOT recommended concurrently with warfarin (brand name Coumarin). The warfarin prescribing information (aka PI: the *official*, FDA-approved information that accompanies the product) describes how the drug is metabolized by the cytochrome P450 pathway. The furanocoumarin compounds in grapefruit interfere with the enzymes in the P450 cascade. Thus, grapefruit consumption will cause warfarin to remain in your body longer (because warfarin metabolism is delayed for up to 72 hours after eating/drinking the grapefruit), and your PT/INR level will rise.
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... replacement of his aortic heart valve. Is there a study of the effectiveness of Plavix and a baby aspirin instead? (had problems with coumadin)
1 answer • 11 Mar 2010
I'm building a list of Drugs that interact with Coumadin. I've had a few bad internal bleeds that almost took my life. I have the list ...
1 answer • 18 Aug 2010
Compatibility of administering the medications together and not causing a problem with the clotting times of the coumadin?
3 answers • 18 Mar 2011
Coumadin - I am 33 years old I had a aortic mechanical heart valve replacement 03/10/2020 and I have
1 answer • 18 Apr 2012
Prosthetic Heart Valves - I'm taking coumadin daily because of my two mechanical heart valves. As a?
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2 answers • 14 Jan 2013