I've recently started Seroquel XR for Borderline Personality Disorder (mainly for extreme anxiety/mood swings, dissociation, paranoia, self-harm urges). I'm taking 50mg in the evening. It's very sedating, which is fine to a point (I often have trouble sleeping due to anxiety), but I am looking forward to the sedation decreasing a little bit as I get more used to the drug.

My main question is: what is the best balance between efficacy for these symptoms and the side effects (specifically, weight gain and sedation)? Are most people taking 100mg/day? Is 50mg enough to help? I am very conscious of weight gain (this is my biggest fear with this drug), but I'm willing to do some work to keep the pounds off if it's helping a lot with the BPD symptoms.