I recently came down with some stomach issues. For the first time in many years, I started having great anxiety again. I'm pretty sure the anxiety is caused by the health issues with my stomach. Have had several doctor visits, and just this last week they finally drew blood for lab work. I started taking Passion Flower Extract, capsule form, about 30 days ago. Taking the recommended amount of 2 in the morning and 2 in the evening. While I know it has helped somewhat, I am not fully relieved of the anxiety. Before starting the Passion Flower, I could not leave my house. Now I can go to the store, but have to have someone with me at all times. At the last visit with doctor, I was prescribed Celexa, or Citalopram. The doctor highly recommended I get ahold of the anxiety before going further with testing for the stomach issues. So my question is, are there any known negative or positive interactions with Passion Flower and Citalopram? I am hesitant to stop the Passion Flower as it has helped somewhat, and I think it takes anywhere from 2 to 4 weeks for herbal supplements to show. Thank you so much for a place to write my question!
25 Feb 2011
It was not possible to check the pharmacological interaction between these two substances as passion flower is not in the list. However, I did want you to read the following:
The pharmacological activity of Passiflora is attributed primarily to the alkaloids and falvonoids. The harmala alkaloids inhibit monoamine oxidase, which may account for part of their pharmacologic effects. Harmala alkaloids include harmine, harmaline, and harmalol. Different parts of the plant and different species have varying amounts of the active alkaloids. The official passion flower is considered to be P. incarnate, which is used for the drug.
What I want to point out is the harmala alkaloids that inhibit monoamine oxidase. Monoamine oxidase inhibitors (MAOI) should not be taken with Celexa. An example of a MAOI is Parnate. If you check the interaction between Parnate and Celexa, it is not to be taken togther. Whether Passion Flower should be taken with Celexa, I can not say for sure, as I am not a pharmacist, but I would contact my pharmacist or doctor before continuing with this combination. Be sure the doctor or the pharmacist is aware that Passion Flower is a MAOI.
Best of luck to you,
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2 answers • 13 Sep 2011