Am taking Spireva and Combivent for COPD (emphysema) any danger of duplication of coverage?

7 Apr 2010

No, there shouldn't be any problems in using these together ... so long as they aren't used at the same time ... and each used at it's minimum dosage.

Theoretically, the potential exists for additive anticholinergic effects such as mydriasis, blurred vision, heat intolerance, fever, dry mouth, tachycardia, urinary retention, and constipation when ipratropium, oxitropium or tiotropium is used with each other or other agents with anticholinergic properties (e.g., antihistamines, antispasmodics, neuroleptics, phenothiazines, skeletal muscle relaxants, tricyclic antidepressants, class IA antiarrhythmics especially disopyramide). However, due to the poor systemic absorption of ipratropium, oxitropium, and tiotropium when administered locally, the interaction would be unlikely at regularly recommended dosages.

http://www.drugs.com/interactions-check.php