I've done methanphetmine quit a bit but not for 17 months. I've heard it screws with your dopamine. If you think you may have adhd like i think i may and have been told by several people i do . Do you guys think it would be stupid to try cymbalta and adderal . Or is anyone on this regimine?
6 Jul 2011
I take 60mg cymbalta and usually 20mg adderall a day. When I first started adderall I only took 5mg 4x a day bc taking it all at once did make me jittery. I also experienced shallow breathing like there was an elephant on my chest. But within a couple weeks it didn't seem to bother me at all and helped with my fatigue. Im not sure if it interferes with the effectiveness of the cymbalta, but I dont think it will hurt you if you take both at the dosage recommended by you doctor. I wouldnt recommend starting them both at the same time tho, bc you prob would experience the side effects to a stronger degree. I was on the cymbalta for several months bf adding adderall. Hope this helps...
16 Feb 2012
I don't want this to be taken unkindly... but have you actually been tested for ADHD or are just going by what others say? Depression and ADHD often do seem to go together (I have major depression and ADHD- been tested as a child and adult for it) but sometimes the symptoms of something else can make you seem ADD too. Ask your doc about the ADHD, and see what s/he says. There are anti-depressives that can be taken with Aderall (like Wellbutrin).
6 Jul 2011
The use of Adderall along with a SSRI or SNRI antidepressant is contrindicated because of the following interaction potential:
Though I know of people that take an antidepressant along with the Adderall so it is possible. Best to discuss with the doctor.
16 Feb 2012
I am also taking Adderall (XR) at 40mg per day (which is kinda high for being around 130lbs along with 60 mg Cymbalta.
I also take 1mg of Ativan/Lorazepam (Benzo) a couple of times daily (as needed) and also Buspar (Buspirone) 2x daily. I have been taking these sorts of meds for nearly 10 years (except for the Adderall, that's new) and have literally taken every combo of antidepressant/benzo/tranquilizer/anti-anxiety med available (outside of the more hardcore ones like Lithium and such).
It's because I have OCD, GAD (Anxiety), and Adult ADHD. My symptoms are simply unmanageable. Uppers slow me down, sedatives don't "sedate" me, and antidepressants really don't do much other than alter my mood (meaning sometimes one will ease anxiety but make me more emotional... or the reverse) so I've combined and weaned off of a lot of drugs (under doctor's care, of course).
Anyway. Cymbalta and Adderall aren't the best combo as far as antidepressants go. Only Effexor and Cymbalta work on Norephinephrine as a primary and dopamine and Serotonin as a secondary. All other antidepressants in the same class (ie: Zoloft, Paxil, Lexapro, Luvox, Prozac, etc) work primarily on Serotonin and very little on dopamine and norephinephrine.
The reason Cymbalta and Adderall are warned against is mostly because they are both Norephinephrine drugs. Meaning you're doing double-duty on those brain chemicals and the norepinephrine and dopamine go hand in hand (so double-duty on the dopamine as well). However, the drugs themselves work in a different way on brain chemicals and you mostly need to make sure that you and your doc are working out a dose that isn't too much (as too much will cause anxiety and fight-or-flight responses) or other abnormal reactions. However, the Cymbalta also works on Serotonin (the "feel good" chemical) which is the precursor to melatonin (the sleep chemical), so Cymbalta balances the latter a little bit by encouraging rest/sleep chemicals.
For myself, I'm trying this combo because NONE of the SSRI's have ever helped and they've always made me much worse (any of the Serotonin drugs), while the only antidepressant to give me somewhat of an improvement was Effexor (very similar to Cymbalta), so when I tried Adderall and found it helped various things, I decided maybe I'd try Cymbalta (again) in combo with something different and see what happens.
I also take the tranquilizer ,(Buspar) and frankly, it might as well be a sugar pill. I take them 2x daily because they're supposed to be like a "booster" to your other meds, but I haven't noticed they do anything at all and am probably going to stop taking them.
However, my Lorazepam (Benzo) helps immensely with chilling out at night and resting a little easier (for sleep) and I try to not take them during the day (even though I'm prescribed to take up to 3 per day) because I don't want a high dose dependency.
If you find you're having problems with not enough relaxation and/or problems with the "come down" of Adderall, a low dose of Lorazepam helps immensely (ie: take like a half of a Lorazepam an hour or so before your Adderall normally wears off and it negates most of the mental/physical side effects of the drug wearing off and eases you into the rest of your day much easier).
Sorry this is so long, but I've taken so many different things and know how scary and frustrating it can be to take new things and wait in anticipation for a possible side effect and/or benefit to happen.
If I were you, I'd make sure that you take your Cymbalta in the evenings (for me around 7:30pm because I get up for work at 3:45am and take my first Adderall dose at 5:30am) and your Adderall during the daytime that way you know that you've spaced out the dose of the two meds probably at least 12 hours and have less chance of side effects that way. I would strongly advise against taking them together for any reason, though.
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