i am also prescribed hydrocodone,for arthritis of the spine(dish)as well as clonazepam(anxiety).
45mg mirtazapine,for sleep and depression.the problem,i am sleeping 12 to 13 hrs.to much,help?
- Posted:
- 18 Nov 2009 by graddy tripp
- Topics:
- depression, sleep disorders, mirtazapine, sleep
Answers (6)
18 Nov 2009
Hi Graddy Tripp
Sleep problems are often part of depression, so I'm wondering whether you had them before depression or during?
Mirtazapine can act as a hypnotic (like some sleeping tabs) and clonazepam is a muscle relaxant. It may be that you are on too much medication, or that the doses are too high.
I'd go back to your Dr and tell them what you are experiencing.
Regards
Junior
18 Nov 2009
Hi Graddy,
Been on mirtazapine off and on for several years, when I was up to 45mgs. I was feeling very hung over most of a day. So, they reduced it. I also take xanax 1.0mg a day and now they added 2 more antidepressants, celexa and Abilify. Because, I was'nt feeling really any better. And, I also take a low dose of hydrocodone every day for a shoulder screwed up by a surgeon. I would say that's not uncommon your sleeping so much, I believe it is the mirtazapine because it has a 12 hr half life. I know it's done that to me, too. So, I would certainly talk to your dr. about adjusting this med and maybe adding a different one for the reduction to keep you okay and feeling better. That's my humble opinion. I have to say though, that
20 Nov 2009
everything you are taking has sleep properties (opiates are suposed to make you tired... its opposit for me but w/e and benzo's (not a muscle relaxent even though it does do this) are used for sleep aids very often) and the mirtazapine shouldnt make you drowsy i dont think(didnt see it on side effects list but who knows and my SSRI doesnt make me want to sleep). that seems more like a depression related issue and the only way to deal with that is a set time to sleep and wake up every day to regulate the circadian cycle
Hi Psychmajor,
My doc prescribed Mirtazapine for insomnia which is also a depression related issue. Mirtazaphine is an antidepressant, but used more often to help with sleep disorders. I looked it up after I was prescribed the med! Just thought you might want to know.
26 Jan 2010
Mirtazapine and other tri-cyclic antidepressants often make patients sleep for more than 12 hours. An mild/medium interaction at CYP450 between clonazepam and mirtazapine can make your sleep deeper and longer.
I suggest changing the therapy. The bezodiazepine should stay (clonazepam), but the TCI should be changed to an SSRI, for example fluoxamine, paroxetine, sertraline, venlafaxine, ..etc. These SSRI-s are taken in the morning usually. If you have severe insomnia, a sleeping pill should be added for a shorter period (3-4 weeks). I suggest sporting also! Anyway, please consult with your doctor / pharmacist!
Best Regards,
agoston
Pharmacist
Hi
Agoston did you ever hear that in smaller doses they use remeron as a sleep aid as little as 7.5mg or less at bedtime and when they increase the dose up to that level of 45mg it seems to be more of an energizing agent, im curious if you ever came across that. Could they be having an opposite reaction. Remeron is an interestting antideprresant but it seems some dosage adjustments probably should be made by your doctor. Good luck
Oops, mirtazapine is TETRA-cyclic, not a TRI-cyclic antidepressant; it doesn't fit in the TCl family. Typically insurance puts it in a separate class ("atypical" or "miscellaneous"), because it's not part of any well-understood family of drugs, and often requires much more care than usual when substituting something a little different.
31 Jan 2012
Hello graddy tripp. Not certain when you take the Clonazepam but I'd space them as far apart as possible. The mirtazapine, if possible take it as early as you can, and if you still find you're getting to much sleep, ask your doctor to cut the dose (mirtazapeine). good health and wishes to you,pledge
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Graddy
I have been told by 3 different doctors to take mirtazapine at night specifically cause it will definitely help put you to sleep. True, other cns depressants will also enhance the sedating affect, but I try not to take say my xanax close to the mirtazapine. And, I still think that mirtazapine with it's 12 hour half life, a pharmicist told me this, that at 45 mgs. you could be hanging over to the next day quite a bit. Once this is in my experience, I could not take that 45mg. dose, for this very reason. Just thought I would add this, because, sedation or helping you sleep is a definite effect from mirtazapine, not neccesarily a side effect either.
And, I too, am on hydrocodone at a low dose, just have to be careful when taking it close to the time I take mirtazapine, too. Hope this helps more and please talk to your doctor about dosing and adjusting stuff. Tell him or her, exactly what you've said here and everything that concerns you. Hope things get more even keeled for you.