Prilosec Interactions
There are 224 drugs known to interact with Prilosec (omeprazole), along with 3 disease interactions. Of the total drug interactions, 23 are major, 153 are moderate, and 48 are minor.
- View all 224 medications that may interact with Prilosec
- View Prilosec disease interactions (3)
Most frequently checked interactions
View interaction reports for Prilosec (omeprazole) and the medicines listed below.
- aspirin
- aspirin
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- gabapentin
- gabapentin
- Lasix (furosemide)
- Lasix (furosemide)
- levothyroxine
- levothyroxine
- Lipitor (atorvastatin)
- Lipitor (atorvastatin)
- lisinopril
- lisinopril
- metformin
- metformin
- prednisone
- prednisone
- Synthroid (levothyroxine)
- Synthroid (levothyroxine)
- trazodone
- trazodone
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Prilosec disease interactions
There are 3 disease interactions with Prilosec (omeprazole) which include:
More about Prilosec (omeprazole)
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- Patient tips
- During pregnancy
- Support group
- Drug class: proton pump inhibitors
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.